We are an experimental research group in the Dept. of Laboratory Medicine at the University of California, San Francisco. Our laboratory is focused on using mass spectrometry-based proteomics to discover new biology and therapeutic targets in hematologic malignancies (blood cancers) and genetic disease.

The Perera Lab (www.rushikapereralab.com) at UC San Francisco studies mechanisms via which pancreatic cancer cells reprogram their metabolism and organelle activity, particularly autophagy and lysosome function, in order to grow. We further investigate how these processes are coordinated at the transcriptional level.

Is there additional information on UCSF websites that would be helpful to you? Send us feedback at [email protected]. rushika perera lab ucsf. University of California, San Francisco. Perera LAB Rushika Perera, Ph.D. | rushika.perera@ucsf.edu Assistant Professor in Medicine Department of Anatomy Department of Pathology Helen Diller Family Comprehensive Cancer Center. Rushika grew up in Australia and received her PhD degree from the University of Melbourne and the Ludwig Institute for Cancer Research studying EGFR signaling in Glioblastoma.

Research Identifying Molecular Drivers of Cellular Plasticity in Pancreatic Cancer NIH R01CA240603 Sep 3, 2020 - May 31, 2025 Role: Principal Investigator July 2016 - Perera lab highlighted in the UCSF Pancreas Center Magazine AACR-Pancreatic Cancer Action Network Career Development Award recipients Kian-Huat Lim, Chris Vakoc, Rushika Perera April 2016 - We are in New Orleans for the American Association for Cancer Research (AACR) annual meeting! The Perera Lab (www.rushikapereralab.com) at UC San Francisco studies mechanisms via which pancreatic cancer cells reprogram their metabolism and organelle activity, particularly autophagy and lysosome function, in order to grow. We further investigate how these processes are coordinated at the transcriptional level. We are an experimental research group in the Dept. of Laboratory Medicine at the University of California, San Francisco. Our laboratory is focused on using mass spectrometry-based proteomics to discover new biology and therapeutic targets in hematologic malignancies (blood cancers) and genetic disease.

Research Overview. Our laboratory focuses on the circuitry of the hippocampus and anatomically related regions. We use a combination of techniques, including large scale multielectrode recording, real-time signal processing and targeted optogenetic interventions and behavioral manipulations of awake, behaving animals to understand how the brain learns, remembers and decides.

Our laboratory focuses on the circuitry of the hippocampus and anatomically related regions. We use a combination of techniques, including large scale multielectrode recording, real-time signal processing and targeted optogenetic interventions and behavioral manipulations of awake, behaving animals to understand how the brain learns, remembers and decides. As a Fellow and Instructor there, he trained in Dr. Charles Sawyers' lab and the Genitourinary Service, performing sensitization screens and studying how oncogenic transcription factors give rise to prostate cancer. He joined the UCSF faculty and started the group in late 2018.

UC San Francisco is leading revolutions in health – and those revolutions often start in the lab. From basic science to clinical research, we are constantly pushing scientific boundaries and earning worldwide recognition for our discoveries. A key element of UCSF’s research success is its deeply ingrained culture of collaboration.

Our laboratory is focused on using mass spectrometry-based proteomics to discover new biology and therapeutic targets in hematologic malignancies (blood cancers) and genetic disease. In our lab we study the cancer-specific mechanisms of autophagy-lysosome activation, and how this organellar system contributes to metabolic reprogramming in PDA. We hypothesize that the functional interplay between enhanced cellular trafficking pathways and activation of gene programs that regulate organelle dynamics and function is an essential, previously unrecognized mechanism for tumor My lab has a particular interest in how the lysosome contributes to cancer pathogenesis with a focus on studying pancreatic ductal adenocarcinoma (PDA). our work has identified novel mechanisms mediating constitutive activation of lysosome biogenesis via coordinated transcriptional upregulation of lysosome transcriptional signatures in PDA and in normal physiological contexts. 1) Postdoctoral position to study Cancer Cell Biology and Developmental Biology at UCSF Job description An NIH funded position is immediately available for a postdoctoral fellow to work jointly in the Knox (website) and Perera ( www.rushikapereralab.com ) labs at the University of California, San Francisco.

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Our laboratory is focused on using mass spectrometry-based proteomics to discover new biology and therapeutic targets in hematologic malignancies (blood cancers) and genetic disease. Perera Lab The research of Dr. Rushika Perera’s laboratory in the Center for Vector-Borne Infectious Diseases (CVID), is focused on understanding the impact of cellular metabolism on the replication of mosquito- and tick-borne flaviviruses within their vertebrate hosts and Arthropod vectors. Welcome to the Keiser Lab @ UCSF. Our lab combines machine learning and chemical biology methods to investigate how small molecules perturb protein networks to achieve therapeutic effects.

rushika perera lab ucsf. University of California, San Francisco.
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The Perera LAB. Department of Anatomy University of California, San Francisco 513 Parnassus Ave, HSW 1301 San Francisco, CA 94143. rushika.perera@ucsf.edu. lab twitter: @rushika_perera. Administrative Assistant: Andy Dang andy.dang@ucsf.edu. Follow us on Twitter: @rushika_perera ©

our work has identified novel mechanisms mediating constitutive activation of lysosome biogenesis via coordinated transcriptional upregulation of lysosome transcriptional signatures in PDA and in normal physiological contexts. 1) Postdoctoral position to study Cancer Cell Biology and Developmental Biology at UCSF Job description An NIH funded position is immediately available for a postdoctoral fellow to work jointly in the Knox (website) and Perera ( www.rushikapereralab.com ) labs at the University of California, San Francisco.

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Walter Lab at UCSF Our laboratory seeks a molecular understanding of how cells control the quality of their proteins and organelles during homeostasis and stress. We are identifying the machinery and mechanisms that ensure proper protein synthesis, folding, and targeting, as well as the pathways that allow organelles to communicate and regulate their abundance.

We use a combination of techniques, including large scale multielectrode recording, real-time signal processing and targeted optogenetic interventions and behavioral manipulations of awake, behaving animals to understand how the brain learns, remembers and decides. As a Fellow and Instructor there, he trained in Dr. Charles Sawyers' lab and the Genitourinary Service, performing sensitization screens and studying how oncogenic transcription factors give rise to prostate cancer. He joined the UCSF faculty and started the group in late 2018.